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Brief overview of epilepsy
Epilepsy is a common neurological disorder, with a lifetime risk of about 0.5%. It is characterized by unpredictable seizures that usually begin in childhood. Seizures are episodes of brain dysfunction caused by excessive and synchronous neuronal activity in the brain.
Seizures may be associated with loss of consciousness (absence seizures) or convulsions (convulsive seizures). Other types of seizure include myoclonic seizures, where groups or clusters of muscle contractions occur, as well as atonic seizures, where muscles become floppy and weak for a short period of time.
Causes of epilepsy
The causes of epilepsy can be divided into two groups:
Inherited disorders. These are genetic conditions that may cause epilepsy. They include:
- Diseases of the brain and nervous system, such as injuries or infections.
- Stroke (cerebrovascular accident).
- Head injury.
- Brain tumor.
- Degenerative diseases such as Alzheimer’s disease and Parkinson’s disease.
Treatment for epilepsy
Treatment for epilepsy aims to control the symptoms and prevent seizures from happening. The main treatments are medicines and surgery.
Medicines for epilepsy work by stopping or reducing the number of seizures you have. They include:
Antiepileptic drugs (AEDs) – these are taken regularly to prevent seizures from happening and help control symptoms if they do happen
Probiotics – these are good bacteria found in foods such as yogurt or taken as capsules or tablets, which may help reduce the number of seizures in some people with epilepsy
What is juvenile myoclonic epilepsy?
Juvenile myoclonic epilepsy is a genetic disorder that causes seizures. It’s rare and affects both males and females equally.
About juvenile myoclonic epilepsy
Juvenile myoclonic epilepsy is a genetic disorder that causes seizures. It’s rare and affects both males and females equally.
The first seizure usually occurs before age 20, but they can start at any age. Seizures are often triggered by sleep deprivation or stress. They may also be triggered by alcohol or drug use, or by skipping meals.
Signs and symptoms of juvenile myoclonic epilepsy
Seizures in juvenile myoclonic epilepsy usually begin with a brief intense jerk of one side of the body (focal onset), which may spread to other parts of the body (generalized onset). The jerks may occur during sleep or when waking up from sleep (nocturnal). They can happen several times a day or less often over many days (episodic). In some people, seizures occur only once during their lifetime (unprovoked). In others, there may be an increase in frequency over time (progressive).
Seizure Types in juvenile myoclonic epilepsy
The most common type of seizure is the myoclonic seizure, which involves a quick, shock-like contraction of a group of muscles. It may be accompanied by loss of consciousness. This type of seizure may occur multiple times during a single day or over a period of months or years.
Atonic seizures are another type of seizure that occurs in JME. Atonic seizures involve sudden loss of muscle tone, causing the person to collapse and fall to the ground. The person remains unconscious for several seconds to minutes after losing muscle tone.
The third type of seizure that can occur in JME is atypical absence seizures (AAS). During an AAS, the person appears to stare off into space without blinking or moving for 30 seconds or longer. However, unlike generalized tonic-clonic seizures (GTCS), there is no loss of muscle tone during this type of seizure.
What can trigger seizures in people with juvenile
myoclonic epilepsy?
There are many factors that can trigger seizures in people with juvenile myoclonic epilepsy. Some of these triggers include:
- Sleep deprivation (lack of sleep)
- Sleep problems are very common in people with JME. Sleep deprivation can lead to seizures. If you have this condition, it’s important to have a good bedtime routine and get enough sleep at night.
- Fatigue or over-exertion
- Excessive physical exertion or extreme fatigue can make you more likely to have a seizure. This is why it’s important to pace yourself when you’re tired or overworked.
- Traveling by car or plane
- Changes in altitude may trigger seizures in some people with JME. If you travel by car or plane, take extra care when traveling through mountains or flying at high altitudes. Also, if you fly frequently for work, try to take breaks while flying so that you don’t get too tired during long flights.
Is juvenile myoclonic epilepsy inherited?
Juvenile myoclonic epilepsy is a genetic condition that is passed down through families. This means that an identical twin of someone with juvenile myoclonic epilepsy has a 50% chance of having the condition too. However, juvenile myoclonic epilepsy has no gender bias and so can affect both males and females.
The inheritance pattern for juvenile myoclonic epilepsy is called autosomal dominant. This means that only one parent needs to have the gene for the condition to be passed on to their children. If you have juvenile myoclonic epilepsy, there is a 50% chance that each of your children will inherit it too.